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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 91244Generated: October 26, 2026

Acetic Acid → (9-(4-Chloro-3-(2-hydroxyethyl)benzyl)-1-oxa-4,9-diazaspiro[5.5]undecan-4-yl)(2-isopropylthiazol-4-yl)methanone

https://huagongshe.com/reaction/91244

Reaction equation

Participants

RoleNameHCIDCharge
ReactantAcetic AcidHCID 176—
ReactantBicarbonate IonHCID 769—
ReactantSodium ionHCID 923—
ReactantTrifluoroacetic acidHCID 6422—
ReactantN-methyl-2-pyrrolidoneHCID 13387—
ReactantTriacetoxyborohydrideHCID 2724942—
Reactant4-Chloro-3-(2-hydroxyethyl)benzaldehydeHCID 57989047—
Reactant(2-Isopropylthiazol-4-yl)-(1-oxa-4,9-diazaspiro[5.5]undecan-4-yl)methanoneHCID 57989152—
Product(9-(4-Chloro-3-(2-hydroxyethyl)benzyl)-1-oxa-4,9-diazaspiro[5.5]undecan-4-yl)(2-isopropylthiazol-4-yl)methanoneHCID 57989207—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (2/10)
ORD IDord-d0813de45c064308a6966db7001d2107
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (2/10)