HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl iodide → (S)-tert-butyl 1-methyl-2-oxoazepan-3-ylcarbamate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl iodide | HCID 6328 | — |
| Reactant | (S)-tert-Butyl (2-oxoazepan-3-yl)carbamate | HCID 7022178 | — |
| Product | (S)-tert-butyl 1-methyl-2-oxoazepan-3-ylcarbamate | HCID 60110341 | — |
Reaction Steps
(S)-tert-butyl 1-methyl-2-oxoazepan-3-ylcarbamate was prepared from (S)-tert-butyl 2-oxoazepan-3-ylcarbamate (Example 8) and methyl iodide according to the general procedure of Example 9. The crude product was purified by column chromatography, eluting with 50% ethyl acetate/hexanes, to provide compound (2e) in 48% yield.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08026233B2 |
| Source dataset | uspto-grants-2011_09 |
| ORD ID | ord-9f0d9d2e4b70443b888feff9bec15f44 |
| Source note | uspto-grants-2011_09 |