HCID 19709298, compound → HCID 24815840, compound

HRID 912551Notes

Reaction equation

HRID 912551 reaction equation
[Cl:1][C:2]1[C:7]([O:8][CH3:9])=[CH:6][C:5]([O:10][CH3:11])=[C:4]([CH3:12])[C:3]=1[NH:13][C:14]1[C:19]([C:20]2[CH:25]=[C:24]([NH2:26])[N:23]=[CH:22][N:21]=2)=[CH:18][N:17]=[CH:16][N:15]=1.NC1N=C[C:31]2[N:36]=[CH:35][N:34]=[CH:33][C:32]=2N=1>>[Cl:1][C:2]1[C:7]([O:8][CH3:9])=[CH:6][C:5]([O:10][CH3:11])=[C:4]([CH3:12])[C:3]=1[NH:13][C:14]1[C:19]([C:20]2[CH:25]=[C:24]([NH:26][C:2]3[CH:3]=[CH:4][C:32]([CH2:31][N:36]4[CH2:35][CH2:9][O:8][CH2:7][CH2:6]4)=[CH:33][N:34]=3)[N:23]=[CH:22][N:21]=2)=[CH:18][N:17]=[CH:16][N:15]=1

Participants

3

Reactant 2

HCID 19709298HCID 19709298, compoundHCID 59486260HCID 59486260, compound

Product 1

HCID 24815840HCID 24815840, compound

Procedure

Compound 32 is carried out the same reaction as in Scheme 1 for compound 10 to afford N4′-(2-Chloro-3,5-dimethoxy-6-methyl-phenyl)-N6-(5-morpholin-4-ylmethyl-pyridin-2-yl)-[4,5′]bipyrimidinyl-6,4′-diamine as final product.

Sources & evidence

ORD record
ord-c3bc13a4a31041479104aef3481440a3
Source dataset
uspto-grants-2011_09
Patent number
US08026243B2

Reaction notes

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