HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetic Anhydride → N-(3,5-dimethoxyphenyl)acetamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetic Anhydride | HCID 7918 | — |
| Reactant | Hexane | HCID 8058 | — |
| Reactant | 3,5-Dimethoxyaniline | HCID 66301 | — |
| Solvent | Toluene | HCID 1140 | — |
| Product | N-(3,5-dimethoxyphenyl)acetamide | HCID 702039 | — |
Reaction Steps
To a solution of 3,5-dimethoxy-phenylamine (d) (22.0 g, 143.6 mmol) in toluene (100 mL), Ac2O (14 mL) is added slowly at room temperature. After stirring 30 min, hexane (50 mL) is added with stirring at rt. The resulting solid is filtered and washed with hexane (50 mL) to offer the title product e as a white solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08026243B2 |
| Source dataset | uspto-grants-2011_09 |
| ORD ID | ord-fe2e4e91013b4f3382459ad94f87d350 |
| Source note | uspto-grants-2011_09 |