HCID 67411071, compound → HCID 59614552, compound

Participants

Reaction Steps

step 5—A mixture of 148 (0.100 g, 0.162 mmol), Pd/C (30 mg) and EtOAc was stirred under one atmosphere hydrogen for 20 h. The catalyst was filtered and washed with EtOAc. The filtrate was concentrated and the crude product purified by SiO2 chromatography eluting with an EtOAc/hexane gradient (30 to 80% EtOAc) to afford 25 mg (29.3%) of I-47.

Provenance & Evidence