HCID 61256357, compound → HCID 86631138, compound

HRID 912704Notes

Reaction equation

HRID 912704 reaction equation
[CH2:1]([O:5][C:6]1[CH:11]=[CH:10][N:9]=[C:8]([CH2:12][OH:13])[CH:7]=1)[CH2:2][CH2:3][CH3:4]>[O-2].[O-2].[Mn+4]>[CH2:1]([O:5][C:6]1[CH:11]=[CH:10][N:9]=[C:8]([CH:12]=[O:13])[CH:7]=1)[CH2:2][CH2:3][CH3:4]

Participants

3

Reactant 1

HCID 61256357HCID 61256357, compound

Product 1

HCID 86631138HCID 86631138, compoundYield 83.1%

Reagents, catalysts & solvents 1

HCID 178418406HCID 178418406, compoundCatalyst

Procedure

The title compound was prepared in accordance with the general method described in Example 17(d) using (4-butoxypyridin-2-yl)methanol (0.82 g, 4.50 mmol, obtained from Example 18(c)) and activated manganese dioxide (3.50 g, 40.5 mmol). 0.67 g of title compound (82% yield) was obtained as a colorless oil.

Workup

  1. customThe title compound was prepared in accordance with the general method

Sources & evidence

ORD record
ord-87aef26d69e4426c99a3effab584efb4
Source dataset
uspto-grants-2011_09
Patent number
US08026244B2

Reaction notes

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