1-Methyl-1H-indole-3-carbaldehyde → 3-(2-{[(1-Methyl-1H-indol-3-yl)methyl]amino}ethyl)-2-thioxo-1,2,3,7-tetrahydro-6H-purin-6-one

Participants

Reaction Steps

The title compound was prepared in accordance with the general method described in Example 26(c) by using 3-(2-aminoethyl)-2-thioxo-1,2,3,7-tetrahydro-6H-purin-6-one trifluoroacetate (98 mg, 0.3 mmol, obtained from Example 26(b)) and 1-methylindole-3-aldehyde (51 mg, 0.03 mmol) which yielded 0.021 g (20% yield) of the title compound.

Provenance & Evidence