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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 912723Generated: November 2, 2026

Triethylamine → HCID 24855163, compound

https://huagongshe.com/reaction/912723

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTriethylamineHCID 8471—
Reactant4-QuinolinecarboxaldehydeHCID 78072—
ReactantSodium cyanoborohydrideHCID 5003444—
ReactantHCID 86631146HCID 86631146—
ProductHCID 24855163HCID 2485516314.1%

Reaction Steps

The title compound was prepared in accordance with the general method described in Example 26(c) by using 3-[2-(methylamino)ethyl]-2-thioxo-1,2,3,7-tetrahydro-6H-purin-6-one trifluoroacetate (0.10 g, 0.29 mmol, obtained from Example 28(c)), triethylamine (0.032 mL, 0.32 mmol), 4-quinoline carboxaldehyde (0.060 g, 0.38 mmol) and sodium cyanoborohydride (0.028 g, 0.44 mmol) which yielded 0.015 g (14% yield) of the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08026244B2
Source datasetuspto-grants-2011_09
ORD IDord-f6f76adcc1ba4427ba28bdb490ce3b2f
Source noteuspto-grants-2011_09