HuagongsheHuagongshe Chemistry Print Report · For research reference only
Piperazine → 1-(3,5-Dichloropyridin-2-yl)piperazine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Piperazine | HCID 4837 | — |
| Reactant | Pyridine, 2,3,5-trichloro- | HCID 27666 | — |
| Product | 1-(3,5-Dichloropyridin-2-yl)piperazine | HCID 2771431 | — |
Reaction Steps
Piperazine (256 mg, 3.0 mmol, Aldrich) and 2,3,5-trichloropyridine (364 mg, 20 mmol, Aldrich) were reacted under the conditions of Example 3a to give the title compound as a light-yellow solid. MS (ESI, pos. ion) m/z: 232 (M+1).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08026241B2 |
| Source dataset | uspto-grants-2011_09 |
| ORD ID | ord-4b7869660ff34fb9b077f0c3b41bf187 |
| Source note | uspto-grants-2011_09 |