HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
1-(3,5-Dichloropyridin-4-yl)piperazine → 6-tert-Butyl-2-[4-(3,5-dichloropyridin-4-yl)piperazin-1-yl]-1H-benzoimidazole
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 1-(3,5-Dichloropyridin-4-yl)piperazine | HCID 2799984 | — |
| Edukt | 6-tert-Butyl-2-chloro-1H-benzoimidazole | HCID 11586517 | — |
| Produkt | 6-tert-Butyl-2-[4-(3,5-dichloropyridin-4-yl)piperazin-1-yl]-1H-benzoimidazole | HCID 57835077 | — |
Reaktionsschritte
The 6-tert-butyl-2-chloro-1H-benzoimidazole (209 mg, 1 mmol, Example 17b) and 1-(3,5-dichloropyridin-4-yl)piperazine (464 mg, 2 mmol, Maybridge) reacted under the conditions of Example 1d to give the title compound as a white amorphous solid. MS (ESI, pos. ion) m/z: 404 (M+1).
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US08026241B2 |
| Quelldatensatz | uspto-grants-2011_09 |
| ORD ID | ord-523a4667b9d4493198080fc46799c919 |
| Quellennotiz | uspto-grants-2011_09 |