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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 912793Generated: November 1, 2026

Piperazine → 2-(1-piperazinyl)-8-Quinolinol

https://huagongshe.com/reaction/912793

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPiperazineHCID 4837—
Reactant2-Chloroquinolin-8-olHCID 274878—
Product2-(1-piperazinyl)-8-QuinolinolHCID 67402375—

Reaction Steps

The quinoline from step (a) above (0.18 g, 1 mmol) and piperazine (0.172 g, 2 mmol, Aldrich) reacted under the conditions of Example 3a to give the title compound as a white solid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08026241B2
Source datasetuspto-grants-2011_09
ORD IDord-fb41925256fb4855bed85e1dcdc002a5
Source noteuspto-grants-2011_09