Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
2,3-Dichloropyridine → HCID 178461514, 화합물
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 2,3-Dichloropyridine | HCID 16988 | — |
| 반응물 | Diisopropylethylamine | HCID 81531 | — |
| 반응물 | HCID 178461512 | HCID 178461512 | — |
| 생성물 | HCID 178461514 | HCID 178461514 | — |
반응 단계
A mixture of 2,3-dichloro-pyridine (44 mg, 0.3 mmol, Aldrich), 7-chloro-2-[(3R)-3-methylpiperazin-1-yl]-5-(trifluoromethyl)-1H-benzoimidazole (80 mg, 0.25 mmol, Example 48a) and N,N-diisopropylethylamine (0.1 mL, 0.58 mmol, Aldrich) reacted under the conditions of Example 48b to give the title compound as a white amorphous solid. MS (ESI, pos. ion) m/z: 430 (M+1).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08026241B2 |
| 출처 데이터셋 | uspto-grants-2011_09 |
| ORD ID | ord-e2962fa34b4c4db3a68090989c55ebf0 |
| 출처 메모 | uspto-grants-2011_09 |