HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-chloro-6-(trifluoromethyl)-4-(3,4,5-trifluorophenyl)-1H-benzoimidazole → HCID 178505442, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-chloro-6-(trifluoromethyl)-4-(3,4,5-trifluorophenyl)-1H-benzoimidazole | HCID 11638867 | — |
| Reactant | 1-(3-Bromopyridin-2-yl)piperazine | HCID 13298529 | — |
| Product | HCID 178505442 | HCID 178505442 | — |
Reaction Steps
2-Chloro-6-(trifluoromethyl)-4-(3,4,5-trifluorophenyl)-1H-benzoimidazole (140 mg, 0.4 mmol, Example 51b) reacted with 1-(3-bromo-pyridin-2-yl)-piperazine (120 mg, 0.5 mmol, Example 41a) under the conditions of Example 3c to give the title compound as a white amorphous solid. MS (ESI, pos. ion) m/z: 556 (M+1).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08026241B2 |
| Source dataset | uspto-grants-2011_09 |
| ORD ID | ord-4945cfa8e8e14af5b62997cf7cd845b8 |
| Source note | uspto-grants-2011_09 |