HuagongsheHuagongshe Chemistry Print Report · For research reference only
Piperazine → 2-Piperazin-1-yl-pyridine-3-sulfonic acid methylamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Piperazine | HCID 4837 | — |
| Reactant | Diisopropylethylamine | HCID 81531 | — |
| Reactant | 2-chloro-N-methylpyridine-3-sulfonamide | HCID 3294054 | — |
| Product | 2-Piperazin-1-yl-pyridine-3-sulfonic acid methylamide | HCID 67401356 | — |
Reaction Steps
A mixture of 2-chloro-N-methyl-3-pyridinesulfonamide (1 g, 4.8 mmol, Specs), piperazine (0.43 g, 5 mmol) and N,N-diisopropylethylamine (1 mL, 5.8 mmol, Aldrich) was reacted under the conditions of Example 41a to give the title compound as a white amorphous solid. MS (ESI, pos. ion) m/z: 257 (M+1).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08026241B2 |
| Source dataset | uspto-grants-2011_09 |
| ORD ID | ord-832deefac2384d33842b1d942f802c87 |
| Source note | uspto-grants-2011_09 |