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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 912833Generated: October 31, 2026

(5-Chloro-6-(piperazin-1-yl)pyridin-3-yl)methanol → HCID 178519829, compound

https://huagongshe.com/reaction/912833

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(5-Chloro-6-(piperazin-1-yl)pyridin-3-yl)methanolHCID 11514124—
Reactant1H-Benzimidazole, 2-chloro-7-iodo-5-(trifluoromethyl)-HCID 67401406—
ProductHCID 178519829HCID 178519829—

Reaction Steps

The benzoimidazole from step (c) above (69 mg, 0.2 mmol) reacted with (5-chloro-6-piperazin-1-yl-pyridin-3-yl)methanol (68 mg, 0.3 mmol, Example 60c) under the conditions of Example 3c to give the title compound as a yellow amorphous solid. MS (ESI, pos. ion) m/z: 538 (M+1).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08026241B2
Source datasetuspto-grants-2011_09
ORD IDord-74a6c5e1d00f491099ea448abafe0fa7
Source noteuspto-grants-2011_09