HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Bromo-2-chloropyridine → (3S)-1-(3-bromopyridin-2-yl)-3-methylpiperazine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Bromo-2-chloropyridine | HCID 693324 | — |
| Reactant | 2-Methylpiperazine, (S)- | HCID 2734219 | — |
| Product | (3S)-1-(3-bromopyridin-2-yl)-3-methylpiperazine | HCID 11658915 | — |
Reaction Steps
A mixture of 3-bromo-2-chloropyridine (0.76 g, 4 mmol, Aldrich) and (S)-(+)-2-methylpiperazine (0.6 g. 6 mmol, Aldrich) reacted under the conditions of Example 3c to give the title compound as a light-brown solid. MS (ESI, pos. ion) m/z: 256 (M+1).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08026241B2 |
| Source dataset | uspto-grants-2011_09 |
| ORD ID | ord-9684ba9ce9dd4443b505eefc01dfc565 |
| Source note | uspto-grants-2011_09 |