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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 912839Generated: October 29, 2026

2-chloro-6-(trifluoromethyl)-4-(3,4,5-trifluorophenyl)-1H-benzoimidazole → HCID 178461516, compound

https://huagongshe.com/reaction/912839

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-chloro-6-(trifluoromethyl)-4-(3,4,5-trifluorophenyl)-1H-benzoimidazoleHCID 11638867—
ReactantHCID 11658915HCID 11658915—
ProductHCID 178461516HCID 178461516—

Reaction Steps

The piperazine from step (a) above (51 mg, 0.2 mmol) reacted with 2-chloro-6-(trifluoromethyl)-4-(3,4,5-trifluorophenyl)-1H-benzoimidazole (53 mg, 0.15 mmol, Example 51b) under the conditions of Example 3c to give the title compound as a white amorphous solid. MS (ESI, pos. ion) m/z: 570 (M+1).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08026241B2
Source datasetuspto-grants-2011_09
ORD IDord-88a8beba16374b7289693520249ac522
Source noteuspto-grants-2011_09