HuagongsheHuagongshe Chemistry Print Report · For research reference only
2,3-Dichloropyridine → (R)-1-(3-chloropyridin-2-yl)-3-methylpiperazine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2,3-Dichloropyridine | HCID 16988 | — |
| Reactant | 2-Methylpiperazine, (R)- | HCID 7330434 | — |
| Product | (R)-1-(3-chloropyridin-2-yl)-3-methylpiperazine | HCID 11658551 | — |
Reaction Steps
A mixture of 2,3-dichloropyridine (0.74 g, 5 mmol, Aldrich) and (R)-(−)-2-methylpiperazine (0.6 g. 6 mmol, Aldrich) reacted under the conditions of Example 43a to give the title compound as a off-white solid. MS (ESI, pos. ion) m/z: 212 (M+1).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08026241B2 |
| Source dataset | uspto-grants-2011_09 |
| ORD ID | ord-d29170bb44f54b61b6e2d7f59480b51b |
| Source note | uspto-grants-2011_09 |