HRID912850

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID11594585

4-bromo-2-chloro-6-trifluoromethyl-1H -benzoimidazole

C8H3BrClF3N2

HCID11658551

(3R)-1-(3-Chloropyridin-2-yl)-3-methylpiperazine

C10H14ClN3

PRODUCTS

生成物

结构：C[C@@H]1CN(c2ncccc2Cl)CCN1c1nc2cc(C(F)(F)F)cc(Br)c2[nH]1

HCID178461521

未命名化合物

PROCEDURE

实验过程

4-Bromo-2-chloro-6-trifluoromethyl-1H-benzoimidazole (1.2 g, 4 mmol, Example 6b) reacted with (3R)-1-(3-chloropyridin-2-yl)-3-methylpiperazine (0.95 g, 4.5 mmol, Example 74a) under the conditions of Example 3c to give the title compound as a light-yellow solid. MS (ESI, pos. ion) m/z: 474 (M+1).