Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 912853Generated: October 27, 2026

(R)-3-Methyl-1-(3-(trifluoromethyl)pyridin-2-yl)piperazine → HCID 178461517, compound

https://huagongshe.com/reaction/912853

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(R)-3-Methyl-1-(3-(trifluoromethyl)pyridin-2-yl)piperazineHCID 11528875—
Reactant4-bromo-2-chloro-6-trifluoromethyl-1H-benzoimidazoleHCID 11594585—
ProductHCID 178461517HCID 178461517—

Reaction Steps

The piperazine from step (a) above (0.37 g, 1.5 mmol) reacted with 4-bromo-2-chloro-6-trifluoromethyl-1H-benzoimidazole (0.36 g, 1.2 mmol, Example 6b) under the conditions of Example 3c to give the title compound as a white amorphous solid. MS (ESI, pos. ion) m/z: 508 (M+1).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08026241B2
Source datasetuspto-grants-2011_09
ORD IDord-e44a0e5135f24fbc8c1d3926f271b161
Source noteuspto-grants-2011_09