HuagongsheHuagongshe Chemistry Print Report · For research reference only
Phosphorus oxychloride → 2,6-dichloro-5-methyl-1H-1,3-benzodiazole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Phosphorus oxychloride | HCID 24813 | — |
| Reactant | 5-Chloro-6-methyl-1H-benzo[d]imidazol-2(3H)-one | HCID 45077821 | — |
| Product | 2,6-dichloro-5-methyl-1H-1,3-benzodiazole | HCID 67033940 | — |
Reaction Steps
The benzimidazol-2-one from step (a) above (10.6 g, 58 mmol) reacted with POCl3 under the conditions of Example 1c to give the title compound as a brown solid. MS (ESI, pos. ion) m/z: 201.3 (M+1).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08026241B2 |
| Source dataset | uspto-grants-2011_09 |
| ORD ID | ord-32476d10d92b4580b858cdd88da3f1c2 |
| Source note | uspto-grants-2011_09 |