HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-chloro-6-(trifluoromethyl)-1H-benzimidazole → HCID 178474646, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-chloro-6-(trifluoromethyl)-1H-benzimidazole | HCID 337905 | — |
| Reactant | N-{5-Chloro-6-[(3R)-3-methyl-piperazin-1-yl]-pyridin-3-ylmethyl}-acetamide | HCID 67401815 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 178474646 | HCID 178474646 | — |
Reaction Steps
A mixture of 2-chloro-6-trifluoromethyl-1H-benzoimidazole (88 mg, 0.4 mmol, Example 1c) and N-{5-chloro-6-[(3R)-3-methyl-piperazin-1-yl]-pyridin-3-ylmethyl}-acetamide from step (e) above (141 mg, 0.5 mmol) in ethanol (2 mL) reacted under the conditions of Example 3c to give the title compound. MS (ESI, pos. ion) m/z: 467 (M+1).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08026241B2 |
| Source dataset | uspto-grants-2011_09 |
| ORD ID | ord-bdca5bf125354c59a7b71e2692de6b3d |
| Source note | uspto-grants-2011_09 |