HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-(5,6-Dichloropyridin-3-yl)ethan-1-one → 2-(5,6-Dichloropyridin-3-yl)propan-2-ol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-(5,6-Dichloropyridin-3-yl)ethan-1-one | HCID 10198006 | — |
| Reactant | HCID 178418689 | HCID 178418689 | — |
| Product | 2-(5,6-Dichloropyridin-3-yl)propan-2-ol | HCID 77230300 | — |
Reaction Steps
1-(5,6-Dichloro-pyridin-3-yl)-ethanone from step (a) above (300 mg, 1.58 mmol) reacted with MeMgBr (0.79 mL, 2.4 mmol, 3.0 M in ether, Aldrich) under the conditions of Example 154b to give the title compound. MS (ESI, pos. ion) m/z: 206 (M+1).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08026241B2 |
| Source dataset | uspto-grants-2011_09 |
| ORD ID | ord-0269234a008b44eaa2696bae66b1cc77 |
| Source note | uspto-grants-2011_09 |