2,3,4-Trifluorobenzeneboronic acid → HCID 178461532, Verbindung

Beteiligte Stoffe

Rolle	Name	HCID	Einwaage
Edukt	2,3,4-Trifluorobenzeneboronic acid	HCID 2783280	—
Edukt	4-bromo-2-[(2R)-4-(3,5-dichloro-pyridin-2-yl)-2-methyl-piperazin-1-yl]-6-trifluoromethyl-1H-benzoimidazole	HCID 57835191	—
Produkt	HCID 178461532	HCID 178461532	—

Reaktionsschritte

4-Bromo-2-[(2R)-4-(3,5-dichloro-pyridin-2-yl)-2-methyl-piperazin-1-yl]-6-trifluoromethyl-1H-benzoimidazole (204 mg, 0.4 mmol, Example 149b) and 4,5,6-trifluorophenylboronic acid (141 mg, 0.8 mmol, Aldrich) reacted under the conditions of Example 158 to give the title compound. MS (ESI, pos. ion) m/z: 504 (M+1).

Herkunft & Nachweise

DOI	10.6084/m9.figshare.5104873.v1
Patentnummer	US08026241B2
Quelldatensatz	uspto-grants-2011_09
ORD ID	ord-73ef06a2e0804ca597f05730681ef3a5
Quellennotiz	uspto-grants-2011_09