3-(Diethylboryl)pyridine → {5-Chloro-6-[(3R)-3-methyl-4-(7-pyridin-3-yl-5-trifluoromethyl-1H-benzoimidazol-2-yl)-piperazin-1-yl]-pyridin-3-yl}-methanol

Participants

Reaction Steps

{6-[(3R)-4-(7-Bromo-5-trifluoromethyl-1H-benzoimidazol-2-yl)-3-methyl-piperazin-1-yl]-5-chloro-pyridin-3-yl}-methanol (152 mg, 0.3 mmol, Example 151) and 3-diethylboranyl-pyridine (118 mg, 0.6 mmol, Aldrich) reacted under the conditions of Example 158 to give the title compound. MS (ESI, pos. ion) m/z: 503 (M+1).

Provenance & Evidence