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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 913092Generated: October 29, 2026

Hydrochloric Acid → HCID 67400096, compound

https://huagongshe.com/reaction/913092

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantHCID 67401412HCID 67401412—
Solvent1,4-DioxaneHCID 31275—
ProductHCID 67400096HCID 67400096—

Reaction Steps

A solution of 4-(quinolin-2-ylamino)-piperidine-1-carboxylic acid tert-butyl ester (1.00 g, 3.05 mmol) in 4 M HCl in dioxane (100 mL) was stirred at rt for 1 h. The solvent was removed under reduced pressure and the crude product used in the consecutive step without further purification assuming quantitative deprotection and formation of the dihydrochloride salt. MS (ISP): 228.6 [M+H]+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08026255B2
Source datasetuspto-grants-2011_09
ORD IDord-451654431c304eb58c5d715f381d5a14
Source noteuspto-grants-2011_09