Triethylsilane → HCID 86637173, compound

Participants

Reaction Steps

To a solution of ethyl (3-chloro-4-{4-(ethyloxy)-1-hydroxy-3-oxo-9-[(2,2,2-trifluoroethyl)oxy]-1,3-dihydro-2H-benzo[f]isoindol-2-yl}phenyl)acetate-ethyl (3-chloro-4-{4-(ethyloxy)-3-hydroxy-1-oxo-9-[(2,2,2-trifluoroethyl)oxy]-1,3-dihydro-2H-benzo[f]isoindol-2-yl}phenyl)acetate (0.163 g, 0.30 mmol) in trifluoroacetic acid (5 ml) cooled to 0° C., was added triethylsilane (0.07 ml, 0.45 mmol). Stirring continued at 0° C. for 10 minutes and then the mixture was evaporated. The isomers were separated using MDAP (shallow gradient)

Provenance & Evidence