Trifluoroacetic acid → HCID 57971488, compound

Participants

Reaction Steps

A solution of tert-butyl 4-{[5-(2-methoxyphenyl)-1,3,4-oxadiazol-2-yl]methyl}benzoate (86 mg, 0.24 mmol) in methylene chloride (5 mL) was treated with trifluoroacetic acid (3.5 g) and stirred at ambient temperature for 30 minutes. The reaction was evaporated in vacuo to give the title compound as a white solid. 1H NMR (600 MHz, CDCl3) δ 8.09 (d, J=8.5 Hz, 2H), 7.81 (d, J=8.2 Hz, 11H), 7.54 (m, 1H), 7.48 (d, J=8.2 Hz, 2H), 7.06 (m, 2H), 4.41 (s, 2H), 3.93 (s, 3H); ESIMS calcd 311.1 (M++H), found 311.1 (M++H).

Provenance & Evidence