HuagongsheHuagongshe Chemistry Print Report · For research reference only
Tetrahydrofurfurylamine → 4-(2-chloro-4-pyridinyl)-N-[(tetrahydro-2-furanyl)methyl]-2-pyrimidinamine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Tetrahydrofurfurylamine | HCID 253298 | — |
| Reactant | 2-Chloro-4-(2-chloropyridin-4-yl)pyrimidine | HCID 58102691 | — |
| Product | 4-(2-chloro-4-pyridinyl)-N-[(tetrahydro-2-furanyl)methyl]-2-pyrimidinamine | HCID 86646780 | — |
Reaction Steps
The title compound was prepared from 2-chloro-4-(2-chloro-4-pyridinyl)pyrimidine (i.e., the product of Example 6, Step A) and tetrahydrofurfurylamine in the same fashion as described in Example 9, Step A, m.p. 74-75° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08026359B2 |
| Source dataset | uspto-grants-2011_09 |
| ORD ID | ord-e90cc89eae6548cbbfd7b37e0c990257 |
| Source note | uspto-grants-2011_09 |