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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 913420Generated: November 1, 2026

2-(Bromomethyl)-5-(trifluoromethyl)furan → 4-Chloro-2-(difluoromethyl)-1-{[5-(trifluoromethyl)-2-furanyl]methyl}-1H-indole-5-carbonitrile

https://huagongshe.com/reaction/913420

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-(Bromomethyl)-5-(trifluoromethyl)furanHCID 2794605—
Reactant4-chloro-2-(difluoromethyl)-1H-indole-5-carbonitrileHCID 24985632—
Product4-Chloro-2-(difluoromethyl)-1-{[5-(trifluoromethyl)-2-furanyl]methyl}-1H-indole-5-carbonitrileHCID 24985969—

Reaction Steps

Synthesized as described in Example 39 from 4-chloro-2-(difluoromethyl)-1H-indole-5-carbonitrile and 2-(bromomethyl)-5-(trifluoromethyl)furan: MS (ESI) m/z 375 (M+1).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08026262B2
Source datasetuspto-grants-2011_09
ORD IDord-2a2961ea7d69447783ddb93ee90b1a36
Source noteuspto-grants-2011_09