3-Bromo-5-[5-(chloromethyl)-1,3,4-oxadiazol-2-yl]pyridine → 1-{[5-(5-Bromo-3-pyridinyl)-1,3,4-oxadiazol-2-yl]methyl}-2-(difluoromethyl)-1H-indole-4,5-dicarbonitrile

Participants

Role	Name	HCID	Charge
Reactant	3-Bromo-5-[5-(chloromethyl)-1,3,4-oxadiazol-2-yl]pyridine	HCID 28979365	—
Reactant	2-(difluoromethyl)-1H-indole-4,5-dicarbonitrile	HCID 57800341	—
Product	1-{[5-(5-Bromo-3-pyridinyl)-1,3,4-oxadiazol-2-yl]methyl}-2-(difluoromethyl)-1H-indole-4,5-dicarbonitrile	HCID 24983679	—

Reaction Steps

Synthesized as described in Example 23 from 2-(difluoromethyl)-1H-indole-4,5-dicarbonitrile and 3-bromo-5-[5-(chloromethyl)-1,3,4-oxadiazol-2-yl]pyridine: MS (ES) m/z 455 and 457 (M+1 Br isotopes).

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US08026262B2
Source dataset	uspto-grants-2011_09
ORD ID	ord-af561bc5250247b0a4b02ec78833f040
Source note	uspto-grants-2011_09