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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 913467Generated: October 25, 2026

3-(Chloromethyl)-5-(4-methoxyphenyl)-1,2,4-oxadiazole → 1-({5-[4-(Methyloxy)phenyl]-1,2,4-oxadiazol-3-yl}methyl)-4-(trifluoromethyl)-1H-indole-5-carbonitrile

https://huagongshe.com/reaction/913467

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-(Chloromethyl)-5-(4-methoxyphenyl)-1,2,4-oxadiazoleHCID 2797131—
Reactant4-(trifluoromethyl)-1H-indole-5-carbonitrileHCID 67405449—
Product1-({5-[4-(Methyloxy)phenyl]-1,2,4-oxadiazol-3-yl}methyl)-4-(trifluoromethyl)-1H-indole-5-carbonitrileHCID 24984456—

Reaction Steps

Synthesized as described in Example 23 using 4-(trifluoromethyl)-1H-indole-5-carbonitrile and 3-(chloromethyl)-5-[4-(methyloxy)phenyl]-1,2,4-oxadiazole: MS (ES) m/z 399 (M+1).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08026262B2
Source datasetuspto-grants-2011_09
ORD IDord-88ff5222462f40afb84e255a501de0e1
Source noteuspto-grants-2011_09