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HRID 913474作成日：2026年10月25日

3-(Chloromethyl)-5-[4-(trifluoromethyl)phenyl]-1,2,4-oxadiazole → 4-(Trifluoromethyl)-1-({5-[4-(trifluoromethyl)phenyl]-1,2,4-oxadiazol-3-yl}methyl)-1H-indole-5-carbonitrile

https://huagongshe.com/reaction/913474

反応式

関与物質

役割名称HCID仕込み量
反応物3-(Chloromethyl)-5-[4-(trifluoromethyl)phenyl]-1,2,4-oxadiazoleHCID 2736624—
反応物4-(trifluoromethyl)-1H-indole-5-carbonitrileHCID 67405449—
生成物4-(Trifluoromethyl)-1-({5-[4-(trifluoromethyl)phenyl]-1,2,4-oxadiazol-3-yl}methyl)-1H-indole-5-carbonitrileHCID 24984619—

反応手順

Synthesized as described in Example 23 using 4-(trifluoromethyl)-1H-indole-5-carbonitrile and 3-(chloromethyl)-5-[4-(trifluoromethyl)phenyl]-1,2,4-oxadiazole: MS (ES) m/z 437 (M+1).

情報源と証拠

DOI10.6084/m9.figshare.5104873.v1
特許番号US08026262B2
出典データセットuspto-grants-2011_09
ORD IDord-112d8b8acb864e7588172dd2253b352d
出典メモuspto-grants-2011_09