HuagongsheHuagongshe Chemistry Print Report · For research reference only
[5-cyano-4-(trifluoromethyl)-1H-indol-1-yl]acetic acid → 1-({3-[3,5-bis(Trifluoromethyl)phenyl]-1,2,4-oxadiazol-5-yl}methyl)-4-(trifluoromethyl)-1H-indole-5-carbonitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | [5-cyano-4-(trifluoromethyl)-1H-indol-1-yl]acetic acid | HCID 57800132 | — |
| Reactant | HCID 178513327 | HCID 178513327 | — |
| Product | 1-({3-[3,5-bis(Trifluoromethyl)phenyl]-1,2,4-oxadiazol-5-yl}methyl)-4-(trifluoromethyl)-1H-indole-5-carbonitrile | HCID 24984622 | — |
Reaction Steps
Synthesized as described in Example 37 from [5-cyano-4-(trifluoromethyl)-1H-indol-1-yl]acetic acid and N-hydroxy-3,5-bis(trifluoromethyl)benzenecarboximidamide: MS (ES) m/z 503 (M−1).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08026262B2 |
| Source dataset | uspto-grants-2011_09 |
| ORD ID | ord-ccc3b725f9d840b08d117333d710419d |
| Source note | uspto-grants-2011_09 |