HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Methyl-1,2,3-thiadiazole-5-carbohydrazide → 1-{[5-(4-Methyl-1,2,3-thiadiazol-5-yl)-1,3,4-oxadiazol-2-yl]methyl}-4-(trifluoromethyl)-1H-indole-5-carbonitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Methyl-1,2,3-thiadiazole-5-carbohydrazide | HCID 1419752 | — |
| Reactant | [5-cyano-4-(trifluoromethyl)-1H-indol-1-yl]acetic acid | HCID 57800132 | — |
| Product | 1-{[5-(4-Methyl-1,2,3-thiadiazol-5-yl)-1,3,4-oxadiazol-2-yl]methyl}-4-(trifluoromethyl)-1H-indole-5-carbonitrile | HCID 57800159 | — |
Reaction Steps
Synthesized as described in Example 35C from [5-cyano-4-(trifluoromethyl)-1H-indol-1-yl]acetic acid and 4-methyl-1,2,3-thiadiazole-5-carbohydrazide: MS (ES) m/z 391 (M+1).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08026262B2 |
| Source dataset | uspto-grants-2011_09 |
| ORD ID | ord-207490aa3b124f8dad64402c22573801 |
| Source note | uspto-grants-2011_09 |