HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Bromo-2,2-dimethylpropane → 1-(2,2-Dimethylpropyl)-2-methyl-4-(trifluoromethyl)-1H-indole-5-carbonitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Bromo-2,2-dimethylpropane | HCID 12415 | — |
| Reactant | 2-methyl-4-(trifluoromethyl)-1H-indole-5-carbonitrile | HCID 53309346 | — |
| Product | 1-(2,2-Dimethylpropyl)-2-methyl-4-(trifluoromethyl)-1H-indole-5-carbonitrile | HCID 67406146 | — |
Reaction Steps
Synthesized as described in Example 4 using 2-methyl-4-(trifluoromethyl)-1H-indole-5-carbonitrile and 1-bromo-2,2-dimethylpropane: 1H NMR (400 MHz, CDCl3) δ 7.51 (d, J=8.5 Hz, 1H), 7.45 (d, J=8.5 Hz, 1H), 6.59 (s, 1H), 3.94 (s, 2H), 2.49 (s, 3H), 1.01 (s, 9H); MS (ES) m/z 295 (M+1).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08026262B2 |
| Source dataset | uspto-grants-2011_09 |
| ORD ID | ord-3c26ecfcb0694855a5bed44a2cf5eec1 |
| Source note | uspto-grants-2011_09 |