HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Bromo-5-[5-(chloromethyl)-1,3,4-oxadiazol-2-yl]pyridine → 1-{[5-(5-Bromo-3-pyridinyl)-1,3,4-oxadiazol-2-yl]methyl}-2-ethyl-4-(trifluoromethyl)-1H-indole-5-carbonitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Bromo-5-[5-(chloromethyl)-1,3,4-oxadiazol-2-yl]pyridine | HCID 28979365 | — |
| Reactant | 2-ethyl-4-(trifluoromethyl)-1H-indole-5-carbonitrile | HCID 67403819 | — |
| Product | 1-{[5-(5-Bromo-3-pyridinyl)-1,3,4-oxadiazol-2-yl]methyl}-2-ethyl-4-(trifluoromethyl)-1H-indole-5-carbonitrile | HCID 67404991 | — |
Reaction Steps
Synthesized as described in Example 145B from 2-ethyl-4-(trifluoromethyl)-1H-indole-5-carbonitrile and 3-bromo-5-[5-(chloromethyl)-1,3,4-oxadiazol-2-yl]pyridine: MS (ESI): m/z 476 (M−1).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08026262B2 |
| Source dataset | uspto-grants-2011_09 |
| ORD ID | ord-57f3536fda7948d4b347dbb4c5d63f75 |
| Source note | uspto-grants-2011_09 |