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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 913550Generated: October 31, 2026

2-Bromoacetamide → HCID 67405481, compound

https://huagongshe.com/reaction/913550

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-BromoacetamideHCID 69632—
Reactant2-cyclopropyl-4-(trifluoromethyl)-1H-indole-5-carbonitrileHCID 67404472—
ProductHCID 67405481HCID 67405481—

Reaction Steps

Synthesized as described in Example 4 using 2-cyclopropyl-4-(trifluoromethyl)-1H-indole-5-carbonitrile and 2-bromoacetamide: 1H NMR (400 MHz, DMSO-d6) δ 7.82 (d, J=8.4 Hz, 1H), 7.71 (bs, 1H), 7.67 (d, J=8.4 Hz, 1H), 7.35 (bs, 1H), 6.37 (s, 1H), 5.02 (s, 2H), 1.94 (m, 1H), 0.99 (m, 2H), 0.77 (m, 2H); MS (ES) m/z 308 (M+1).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08026262B2
Source datasetuspto-grants-2011_09
ORD IDord-960085f6c321411e98ad3965d20205bf
Source noteuspto-grants-2011_09