N-(4-(2-Bromoethoxy)phenyl)acetamide → N-(4-{[2-(4-Chloro-5-cyano-2-methyl-1H-indol-1-yl)ethyl]oxy}phenyl)acetamide

Participants

Reaction Steps

Synthesized as described in Example 4 from 4-chloro-2-methyl-1H-indole-5-carbonitrile and N-{4-[(2-bromoethyl)oxy]phenyl}acetamide: 1H NMR (400 MHz, DMSO-d6) δ 9.72 (s, 1 H), 7.89 (d, J=1.1 Hz, 1 H), 7.77 (d, J=8.5 Hz, 1 H), 7.53 (d, J=8.5 Hz, 1 H), 7.39 (d, J=8.9 Hz, 2 H), 6.73 (d, J=8.9 Hz, 2 H), 4.62 (t, 2 H), 4.19 (t, 2 H), 2.48 (s, 3 H), 1.95 (s, 3H); MS (ES) m/z 368 (M+1).

Provenance & Evidence