2,4,6-Trifluorobenzoic acid → HCID 57800279, compound

HRID 913629Notes

Reaction equation

HRID 913629 reaction equation
[C:1]([C:3]1[C:4]([C:17]([F:20])([F:19])[F:18])=[C:5]2[C:9](=[CH:10][CH:11]=1)[N:8]([CH2:12][C:13](=[NH:16])[NH:14][OH:15])[CH:7]=[CH:6]2)#[N:2].[F:21][C:22]1[CH:30]=[C:29]([F:31])[CH:28]=[C:27]([F:32])[C:23]=1[C:24](O)=O>>[F:18][C:17]([F:19])([F:20])[C:4]1[C:3]([C:1]#[N:2])=[CH:11][CH:10]=[C:9]2[C:5]=1[CH:6]=[CH:7][N:8]2[CH2:12][C:13]1[N:16]=[C:24]([C:23]2[C:22]([F:21])=[CH:30][C:29]([F:31])=[CH:28][C:27]=2[F:32])[O:15][N:14]=1

Participants

3

Reactant 2

HCID 5203732,4,6-Trifluorobenzoic acidHCID 178509476HCID 178509476, compound

Product 1

HCID 57800279HCID 57800279, compound

Procedure

Synthesized as described in Example 241 from 2-[5-cyano-4-(trifluoromethyl)-1H-indol-1-yl]-N-hydroxyethanimidamide and 2,4,6-trifluorobenzoic acid: MS (ES) m/z 423 (M+1).

Workup

  1. customSynthesized

Sources & evidence

ORD record
ord-25a72da186a84d68ac4afc669ec1b498
Source dataset
uspto-grants-2011_09
Patent number
US08026262B2

Reaction notes

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