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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 913640Generated: October 29, 2026

Methyl 2-bromopropionate → Methyl 2-(5-cyano-4-(trifluoromethyl)-1H-indol-1-yl)propanoate

https://huagongshe.com/reaction/913640

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethyl 2-bromopropionateHCID 95576—
Reactant4-(trifluoromethyl)-1H-indole-5-carbonitrileHCID 67405449—
ProductMethyl 2-(5-cyano-4-(trifluoromethyl)-1H-indol-1-yl)propanoateHCID 57800469—

Reaction Steps

Synthesized as described in Example 4 from 4-(trifluoromethyl)-1H-indole-5-carbonitrile and methyl 2-bromopropanoate: MS (APCl) m/z 297 (M+1).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08026262B2
Source datasetuspto-grants-2011_09
ORD IDord-245fe7b900a443ae92c7f16fd60b01b0
Source noteuspto-grants-2011_09