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Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 913703생성일: 2026년 10월 25일

3,5-Bis-trifluoromethylphenylboronic acid → 1-({2-[3,5-bis(Trifluoromethyl)phenyl]-1,3-thiazol-4-yl}methyl)-2-methyl-4-(trifluoromethyl)-1H-indole-5-carbonitrile

https://huagongshe.com/reaction/913703

반응식

참여 물질

역할이름HCID투입량
반응물3,5-Bis-trifluoromethylphenylboronic acidHCID 156265—
반응물1-[(2-Bromo-1,3-thiazol-4-yl)methyl]-2-methyl-4-(trifluoromethyl)-1H-indole-5-carbonitrileHCID 67404358—
생성물1-({2-[3,5-bis(Trifluoromethyl)phenyl]-1,3-thiazol-4-yl}methyl)-2-methyl-4-(trifluoromethyl)-1H-indole-5-carbonitrileHCID 86620698—

반응 단계

Synthesized as described in Example 310D using 1-[(2-bromo-1,3-thiazol-4-yl)methyl]-2-methyl-4-(trifluoromethyl)-1H-indole-5-carbonitrile (Example 311B) and [3,5-bis(trifluoromethyl)phenyl]boronic acid: MS (ES) m/z 534 (M+1).

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US08026262B2
출처 데이터셋uspto-grants-2011_09
ORD IDord-44642c9b65774cb9b1ef3a43c4562635
출처 메모uspto-grants-2011_09