HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-Chloromethyl-4-methyl-2-(4-trifluoromethyl-phenyl)-thiazole → HCID 86620701, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-Chloromethyl-4-methyl-2-(4-trifluoromethyl-phenyl)-thiazole | HCID 2783006 | — |
| Reactant | 2-methyl-4-(trifluoromethyl)-1H-indole-5-carbonitrile | HCID 53309346 | — |
| Product | HCID 86620701 | HCID 86620701 | — |
Reaction Steps
Synthesized as described in Example 4 using 2-methyl-4-(trifluoromethyl)-1H-indole-5-carbonitrile (Example 120) and 5-(chloromethyl)-4-methyl-2-[4-(trifluoromethyl)phenyl]-1,3-thiazole: 1H NMR (400 MHz, CDCl3) δ 7.87 (d, J=8.0 Hz, 2H), 7.60 (d, J=8.0 Hz, 2H), 7.52 (d, J=7.8 Hz, 1H), 7.45 (d, J=7.8 Hz, 1H), 6.65 (s, 1H), 5.46 (s, 2H), 2.60 (s, 3H), 2.53 (s, 3H); MS (ES) m/z 480 (M+1).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08026262B2 |
| Source dataset | uspto-grants-2011_09 |
| ORD ID | ord-0e4c9b7971cf47ccac2e74d1b3076f09 |
| Source note | uspto-grants-2011_09 |