HCID 46785477, compound → HCID 86620706, compound

HRID 913716Notes

Reaction equation

HRID 913716 reaction equation
[CH3:1][C:2]1[NH:3][C:4]2[C:9]([CH:10]=1)=[C:8]([C:11]([F:14])([F:13])[F:12])[C:7]([C:15]#[N:16])=[CH:6][CH:5]=2.[F:17][C:18]([F:33])([F:32])[C:19]1[CH:20]=[C:21]([C:25]2[S:26][C:27]([CH2:30]Cl)=[CH:28][N:29]=2)[CH:22]=[CH:23][CH:24]=1>>[CH3:1][C:2]1[N:3]([CH2:30][C:27]2[S:26][C:25]([C:21]3[CH:22]=[CH:23][CH:24]=[C:19]([C:18]([F:33])([F:17])[F:32])[CH:20]=3)=[N:29][CH:28]=2)[C:4]2[C:9]([CH:10]=1)=[C:8]([C:11]([F:12])([F:14])[F:13])[C:7]([C:15]#[N:16])=[CH:6][CH:5]=2

Participants

3

Reactant 2

HCID 46785477HCID 46785477, compoundHCID 533093462-methyl-4-(trifluoromethyl)-1H-indole-5-carbonitrile

Product 1

HCID 86620706HCID 86620706, compound

Procedure

Synthesized as described in Example 4 using 2-methyl-4-(trifluoromethyl)-1H-indole-5-carbonitrile (Example 120) and 2-[3-(trifluoromethyl)phenyl]-5-(chloromethyl)-1,3-thiazole (Example 322B): MS (ES) m/z 466 (M+1).

Workup

  1. customSynthesized

Sources & evidence

ORD record
ord-32a78f63e0d04efd9f99b15f8a16104b
Source dataset
uspto-grants-2011_09
Patent number
US08026262B2

Reaction notes

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