HuagongsheHuagongshe Chemistry Print Report · For research reference only
1,3-Dichloroacetone → 2-[3,5-Bis(trifluoromethyl)phenyl]-4-(chloromethyl)-1,3-oxazole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1,3-Dichloroacetone | HCID 10793 | — |
| Reactant | 3,5-Bis(trifluoromethyl)benzamide | HCID 519927 | — |
| Product | 2-[3,5-Bis(trifluoromethyl)phenyl]-4-(chloromethyl)-1,3-oxazole | HCID 57800468 | — |
Reaction Steps
Synthesized as described in Example 353A using 3,5-bis-(trifluoromethyl)benzamide and 1,3-dichloro-2-propanone: 1H NMR (400 MHz, CDCl3) δ 8.50 (s, 2H), 7.96 (s, 1H), 7.80 (s, 1H), 4.59 (s, 2H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08026262B2 |
| Source dataset | uspto-grants-2011_09 |
| ORD ID | ord-cabbcbb71ef84a5ebea92f1ed99f621a |
| Source note | uspto-grants-2011_09 |