HCID 59318574, compound → HCID 131729199, compound

Participants

Reaction Steps

<2> The reaction described in <3> of Synthesis Example 1 was performed under the same conditions, except that the 4-methoxyphenylacetyloxymethyl difluoromethanesulfonic acid sodium salt (0.8 g) produced in <1> of Synthesis Example 4 above was used instead of the benzoyloxymethyldifluorosulfonic acid sodium salt in the reaction with diphenylmethylphenylsulfonium trifluoromethanesulfonic acid sodium salt, and thus 3.95 g (yield 95.9%) of 4-methoxyphenylacetic acid 2,2-difluoro-2-sulfoethyl ester diphenylmethylphenylsulfonium salt as shown in the following reaction scheme 9 was obtained. The structure of the product was confirmed by 1H-NMR (see FIG. 8).

Provenance & Evidence