HCID 59318575, compound → HCID 131729205, compound

HRID 913783Notes

Reaction equation

HRID 913783 reaction equation
[Na+].[CH:2]1[C:15]2[C:6](=[CH:7][C:8]3[C:13]([C:14]=2[C:16]([O:18][CH2:19][C:20]([F:26])([F:25])[S:21]([O-:24])(=[O:23])=[O:22])=[O:17])=[CH:12][CH:11]=[CH:10][CH:9]=3)[CH:5]=[CH:4][CH:3]=1.[Na].FC(F)(F)S([O-])(=O)=O.[C:36]1([CH:42]([SH+:49][C:50]2[CH:55]=[CH:54][CH:53]=[CH:52][CH:51]=2)[C:43]2[CH:48]=[CH:47][CH:46]=[CH:45][CH:44]=2)[CH:41]=[CH:40][CH:39]=[CH:38][CH:37]=1>>[C:43]1([CH:42]([SH+:49][C:50]2[CH:55]=[CH:54][CH:53]=[CH:52][CH:51]=2)[C:36]2[CH:41]=[CH:40][CH:39]=[CH:38][CH:37]=2)[CH:44]=[CH:45][CH:46]=[CH:47][CH:48]=1.[F:26][C:20]([F:25])([S:21]([OH:24])(=[O:23])=[O:22])[CH2:19][O:18][C:16]([C:14]1[C:13]2[C:8]([CH:7]=[C:6]3[C:15]=1[CH:2]=[CH:3][CH:4]=[CH:5]3)=[CH:9][CH:10]=[CH:11][CH:12]=2)=[O:17]

Participants

3

Reactant 2

HCID 59318575HCID 59318575, compoundHCID 131729198HCID 131729198, compound

Product 1

HCID 131729205HCID 131729205, compoundYield 85.6%

Procedure

<2> The reaction described in <3> of Synthesis Example 1 was performed under the same conditions, except that the 9-anthracenecarbonyloxymethyl difluoromethanesulfonic acid sodium salt (3.82 g) produced in <1> of Synthesis Example 9 above was used instead of the benzoyloxymethyldifluorosulfonic acid sodium salt in the reaction with diphenylmethylphenylsulfonium trifluoromethanesulfonic acid sodium salt, and thus 3.86 g (yield 85.6%) of 9-anthracenecarboxylic acid 2,2-difluoro-2-sulfoethyl ester diphenylmethylphenylsulfonium salt as shown in the following reaction scheme 19 was obtained. The structure of the product was confirmed by 1H-NMR.

Workup

  1. custom<2> The reaction described in <3> of Synthesis Example 1
  2. customproduced in <1> of Synthesis Example 9

Sources & evidence

ORD record
ord-7bd04b3e439c47a4850b3ae0fe59f881
Source dataset
uspto-grants-2011_09
Patent number
US08026390B2

Reaction notes

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