HCID 57546152, compound → HCID 57546076, compound

Participants

Reaction Steps

Prepared according to the procedure used to prepare tert-butyl 4-((1-(5-chloro-1H-indazol-7-yl)-2-methoxy-2-oxoethoxy)methyl)-4-(4-fluorophenyl)piperidine-1-carboxylate using 2-((1-(tert-butoxycarbonyl)-4-(4-fluorophenyl)piperidin-4-yl)methoxy)-2-(5-chloro-2-((2-(trimethylsilyl)ethoxy)methyl)-2H-indazol-7-yl)acetic acid as the starting material and using dichloromethane/methanol in its purification. tR=3.03 min (Phenomenex C18 3.0×50 mm, A=90% H2O/10% methanol, B=90% methanol/10% H2O, Modifier 0.1% TFA, 0.00 min=0% B, 3.0 min=100% B, 5.0 min=100% B, Flow rate=4 mL/min). Mass spec.: 518.22 (MH)+.

Provenance & Evidence