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HRID914038

反应详情

EQUATION

反应方程式

HRID 914038 的结构方程式

REACTANTS

反应物

2
结构：COCC(OCC1(c2ccc(F)cc2)CCN(C(=O)OC(C)(C)C)CC1)c1cc(Cl)cc2cn[nH]c12
HCID57546214

未命名化合物

结构：COC(=O)C(OCC1(c2ccc(F)cc2)CCN(C)CC1)c1cc(Cl)cc2cn[nH]c12.O=C(O)C(F)(F)F
HCID67403905

未命名化合物

PRODUCTS

生成物

1
结构：COCC(OCC1(c2ccc(F)cc2)CCN(C)CC1)c1cc(Cl)cc2cn[nH]c12.O=C(O)C(F)(F)F
HCID25161096

未命名化合物

PROCEDURE

实验过程

Prepared according to the procedure used to prepare methyl 2-(5-chloro-1H-indazol-7-yl)-2-((4-(4-fluorophenyl)-1-methylpiperidin-4-yl)methoxy)acetate trifluoroacetic acid salt using tert-butyl 4-((1-(5-chloro-1H-indazol-7-yl)-2-methoxyethoxy)methyl)-4-(4-fluorophenyl)piperidine-1-carboxylate as the starting material. 1H-NMR (CD3OD, 500 MHz) δ 8.48 (s, 0.1H), 8.03 (s, 0.8H), 7.88 (s, 0.1H), 7.70 (m, 0.8H), 7.42 (m, 2H), 6.90-7.40 (m, 3H), 4.77 (m, 1H), 3.87 (m, 0.3H), 3.68 (m, 1H), 3.40-3.63 (m, 4.8H), 2.40-3.00 (m, 7H), 2.12 (m, 2H). Mass spec.: 432.26 (MH)+.

WORKUP

后处理

  1. customPrepared