HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Iodooctane → HCID 67400024, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Iodooctane | HCID 12380 | — |
| Reactant | Acetic Acid Mixture with Hydrobromic Acid | HCID 21893785 | — |
| Reactant | 2-[(4-{2-[(5-Ethylpyrimidin-2-yl)amino]ethyl}-1,3-thiazol-2-yl)thio]-2-methylpropionic acid tert-butyl ester | HCID 59758871 | — |
| Solvent | Diethyl Ether | HCID 3283 | — |
| Product | HCID 67400024 | HCID 67400024 | — |
Reaction Steps
A compound obtained using 2-[(4-{2-[(5-ethylpyrimidin-2-yl)amino]ethyl}-1,3-thiazol-2-yl)thio]-2-methylpropionic acid tert-butyl ester synthesized in Example 265-1 and 1-iodooctane as starting materials and by an operation similar to that of Example 326 was dissolved in diethyl ether, and reacted with 30% hydrobromic acid-acetic acid to give the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08026370B2 |
| Source dataset | uspto-grants-2011_09 |
| ORD ID | ord-bfba4dce35bc4c0da04c5bddb1b95ddb |
| Source note | uspto-grants-2011_09 |